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General and contact information

Howard Judelson's background
education and interests

The oomycetes
learn more about these exciting organisms

The late blight disease
learn more about the problems that P. infestans causes

Research Interests
Ongoing research projects

Other lab members


Opportunities for graduate study in the lab


working in hood

Sharma R, Xia X, Cano LM, Evangelisti E, Kemen E, Judelson H, Oome S, Sambles C, van den Hoogen DJ, Kitner M, Klein J, Meijer HJG, Spring O, Win J, Zipper R, Bode HB, Govers F, Kamoun S, Schornack S, Studholme DJ, van den Ackerveken G, Thines M. 2015. Genome analyses of the sunflower pathogen Plasmopara halstedii provide insights into effector evolution in downy mildews and Phytophthora. BMC Genomics in press.

Matson M.H.E., Small I, Fry WE, Judelson HS. 2015. Metalaxyl resistance in Phytophthora infestans: assessing role of RPA190 gene and diversity within clonal lineages. Phytopathology, in press.

Fry, W., P. Birch, H. Judelson, N. J. Grunwald, G. Danies, K. L. Everts, A. J. Gevens, B. Gugino, D. A. Johnson, S. B. Johnson, M. McGrath, K. L. Myers, J. B. Ristaino, G. A. Secor and C. D. Smart. 2015. Five Reasons to Consider Phytophthora infestans a Reemerging Pathogen. Phytopathology 105:966-81.

Kamoun, S., Furzer, O., Jones, J. D. G., Judelson, H. S., Ali, G. S., Dalio, R. J. D., Roy, S. G., Schena, L., Zambounis, A., Panabieres, F., Cahill, D., Ruocco, M., Figueiredo, A., Chen, X.-R., Hulvey, J., Stam, R., Lamour, K., Gijzen, M., Tyler, B. M., Grunwald, N. J., Mukhtar, M. S., Tome, D. F. A., Tor, M., Van Den Ackerveken, G., McDowell, J., Daayf, F., Fry, W. E., Lindqvist-Kreuze, H., Meijer, H. J. G., Petre, B., Ristaino, J., Yoshida, K., Birch, P. R. J. and Govers, F. 2015. The Top 10 oomycete pathogens in molecular plant pathology. Molecular Plant Pathology, 16: 413-434.

Gamboa-Melendez H, Judelson HS. 2015. Development of a bipartite chemical-inducible gene switch based on the ecdysone receptor for the oomycete Phytophthora infestans. Molecular Plant Pathology 16: 83-91.

Xiang Q, Judelson HS. 2014. Myb transcription factors and light regulate sporulation in the oomycete Phytophthora infestans. PLoS ONE 9: e92086.

Gamboa-Melendez H, Huerta A, Judelson HS. 2013. bZIP transcription factors in the oomycete Phytophthora infestans with novel DNA-binding domains are involved in defense against oxidative stress. Eukaryotic Cell 12: 1403-12.

W. E. Fry, M. T. McGrath, A. Seaman, T. A. Zitter, A. McLeod, G. Danies, I. M. Small, K. Myers, K. Everts, A. J. Gevens, B. K. Gugino, S. B. Johnson, H. Judelson, J. Ristaino, P. Roberts, G. Secor, K. Seebold, Jr., K. Snover-Clift, A. Wyenandt, N. J. Grunwald, and C. D. Smart. 2013. The 2009 Late Blight Pandemic in the Eastern United States, Causes and Results. Plant Disease 97: 296-306.

Roy S, Kagda M, Judelson HS. 2013. Genome-wide Prediction and Functional Validation of Promoter Motifs Regulating Gene Expression in Spore and Infection Stages of Phytophthora infestans. PLoS Pathogens 9:e1003182.

Roy S, Poidevin L, Jiang T, Judelson HS. 2013. Novel core promoter elements in the oomycete pathogen Phytophthora infestans and their influence on expression detected by genome-wide analysis. BMC Genomics 14:106.

Qiao Y, Liu L, Xiong Q, Flores C, Wong J, Shi J, Wang X, Liu X, Xiang Q, Jiang S, Zhang F, Wang Y, Judelson HS, Chen X, Ma W. 2013. Oomycete pathogens encode RNA silencing suppressors. Nature Genetics 45:330-333.

Judelson HS, Shrivastava J, Manson J. 2012. Decay of genes encoding the oomycete flagellar proteome in the downy mildew Hyaloperonospora arabidopsidis. PLoS One 7:e47624.

Judelson HS. 2012. Dynamics and innovations within oomycete genomes: insights into biology, pathology, and evolution. Eukaryotic Cell 11:1304-1312.

Ah-Fong, A. M. V, and Judelson, H. S. (2011) Vectors for fluorescent protein tagging in Phytophthora: tools for functional genomics and cell biology. Fungal Biology 115:882-890.

Ah-Fong, A. M. V, and Judelson, H. S. (2011) New role for Cdc14 phosphatase: localization to basal bodies in the oomycete Phytophthora and its evolutionary coinheritance with eukaryotic flagella. PLoS One 6:e16725.

Baxter L, Tripathy S, Ishaque N, Boot N, Cabral A, Kemen E, Thines M, Ah-Fong A, Anderson R, Badejoko W, Bittner-Eddy P, Boore JL, Chibucos MC, Coates M, Dehal P, Delehaunty K, Dong S, Downton P, Dumas B, Fabro G, Fronick C, Fuerstenberg SI, Fulton L, Gaulin E, Govers F, Hughes L, Humphray S, Jiang RH, Judelson H, Kamoun S, Kyung K, Meijer H, Minx P, Morris P, Nelson J, Phuntumart V, Qutob D, Rehmany A, Rougon-Cardoso A, Ryden P, Torto-Alalibo T, Studholme D, Wang Y, Win J, Wood J, Clifton SW, Rogers J, Van den Ackerveken G, Jones JD, McDowell JM, Beynon J, Tyler BM. (2010) Signatures of adaptation to obligate biotrophy in the Hyaloperonospora arabidopsidis genome. Science 330:1549-51.

Judelson H.S., and Ah-Fong A. M. V. (2010) The kinome of Phytophthora infestans reveals oomycete-specific innovations and links to other taxonomic groups. BMC Genomics 11:e700.

Judelson, H. S., Ah-Fong, A. M. V, and Fabritius, A.-L. (2010) An RNA symbiont enhances heat tolerance and secondary homothallism in the oomycete Phytophthora infestans. Microbiology 156:2026-2034.

Xiang, Q., and Judelson (2010) Myb transcription factors in the oomycete Phytophthora with novel diversified DNA-binding domains and developmental stage-specific expression. Gene 453:1-8.

Haas, B. J., Kamoun, S., Zody, M. C., Jiang, R. H., Handsaker, R. E., Cano, L. M., Grabherr, M., Kodira, C. D., Raffaele, S., Torto-Alalibo, T., Bozkurt, T. O., Ah-Fong, A. M., Alvarado, L., Anderson, V. L., Armstrong, M. R., Avrova, A., Baxter, L., Beynon, J., Boevink, P. C., Bollmann, S. R., Bos, J. I., Bulone, V., Cai, G., Cakir, C., Carrington, J. C., Chawner, M., Conti, L., Costanzo, S., Ewan, R., Fahlgren, N., Fischbach, M. A., Fugelstad, J., Gilroy, E. M., Gnerre, S., Green, P. J., Grenville-Briggs, L. J., Griffith, J., Grunwald, N. J., Horn, K., Horner, N. R., Hu, C. H., Huitema, E., Jeong, D. H., Jones, A. M., Jones, J. D., Jones, R. W., Karlsson, E. K., Kunjeti, S. G., Lamour, K., Liu, Z., Ma, L., Maclean, D., Chibucos, M. C., McDonald, H., McWalters, J., Meijer, H. J., Morgan, W., Morris, P. F., Munro, C. A., O'Neill, K., Ospina-Giraldo, M., Pinzon, A., Pritchard, L., Ramsahoye, B., Ren, Q., Restrepo, S., Roy, S., Sadanandom, A., Savidor, A., Schornack, S., Schwartz, D. C., Schumann, U. D., Schwessinger, B., Seyer, L., Sharpe, T., Silvar, C., Song, J., Studholme, D. J., Sykes, S., Thines, M., van de Vondervoort, P. J., Phuntumart, V., Wawra, S., Weide, R., Win, J., Young, C., Zhou, S., Fry, W., Meyers, B. C., van West, P., Ristaino, J., Govers, F., Birch, P. R., Whisson, S. C., Judelson, H. S., Nusbaum, C. (2009) Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans. Nature 461:393-398.

Judelson, H. S., R. D. Narayan, and S. Tani (2009) Metabolic adaptation of Phytophthora infestans during growth on leaves, tubers, and artificial media. Molecular Plant Pathology, 10:843-855.

Judelson, H. S., and Ah-Fong, A. M. V. (2009) Progress and challenges in oomycete transformation. Pages 435 to 453 In: Oomycete Genetics and Genomics: Diversity, Interactions and Research Tools (K. Lamour and S. Kamoun, eds.), Wiley.

Judelson, H. S. (2009) Sexual Reproduction In Oomycetes: Biology, Diversity, And Contributions To Fitness. Pages 121 to 138 In: Oomycete Genetics and Genomics: Diversity, Interactions and Research Tools (K. Lamour and S. Kamoun, eds.), Wiley.

Xiang, Q., Kim, K. S., Roy, S., and Judelson, H. S. (2009) A motif within a complex promoter from the oomycete Phytophthora infestans determines transcription during an intermediate stage of sporulation. Fungal Genetics and Biology 46, 400-409.

Judelson, H. S., Narayan, R. D., Ah-Fong, A. M. V., and Kim, K. S. (2009) Gene expression changes during asexual sporulation by the late blight agent Phytophthora infestans occur in discrete temporal stages. Molecular Genetics and Genomics 281, 193-206.

Ah-Fong, A. M. V., Bormann-Chung, C. A. and Judelson, H. S. (2008) Optimization of transgene-mediated silencing in Phytophthora infestans and its association with small-interfering RNAs. Fungal Genetics and Biology 45, 1197-1205.

Judelson HS, Ah-Fong AMV, Aux G, Avrova AO, Bruce C, Cakir C, da Cunha L, Grenville-Briggs L, Latijnhouwers M, Ligterink W, Meijer HJG, Roberts S, Thurber CS, Whisson SC, Birch PRJ, Govers F, Kamoun S, van West P, Windass J. (2008) Gene expression profiling during asexual development of the late blight pathogen Phytophthora infestans reveals a highly dynamic transcriptome. Molecular Plant Microbe Interactions 21, 433-547.

Ah Fong, A. M. V., Xiang, Q., and Judelson, H. S. (2007) Architecture of the Sporulation-Specific Cdc14 Promoter from the Oomycete Phytophthora infestans. Eukaryotic Cell 6, 2222-2230.

Judelson, H. S. (2007) Molecular strategies for identifying determinants of oomycete pathogenicity. Pages 383 to 410 In: Molecular Mechanisms of Plant and Microbe Coexistence (P. Dion and C. Nautiyal, eds.). Springer, Heidelberg.

Judelson, H. S. (2007) Sexual reproduction in plant pathogenic oomycetes: biology and impact on disease. Pages 445-458 in: Sex in fungi: molecular determination and evolutionary implications (J. Heitman, J. Kronstad, J. Taylor, L. Casselton, eds.). ASM Press, Washington DC.

Judelson, H. S., and Tani, S. (2007) Transgene-induced silencing of the zoosporogenesis-specific PiNIFC gene cluster of Phytophthora infestans involves chromatin alterations. Eukaryotic Cell 6, 1200-1209

Prakob, W. and Judelson, H. S. (2007) Gene expression during oosporogenesis in heterothallic and homothallic Phytophthora. Fungal Genet. Biol. 44, 726-739

Judelson, H. S., Narayan, R., Ah Fong, A. M. V., and Tani, S. (2007) Performance of a tetracycline-responsive transactivator system for manipulating gene expression in the oomycete Phytophthora infestans. Current Genetics 51, 297-307

Judelson, H. S. (2007) Genomics of the plant pathogenic oomycete Phytophthora: insights into biology and evolution. Advances in Genetics 57, 97-141.

Judelson, H. S. and Ah Fong, A. M. V. (2007) Genomics of oomycetes. Pages 1-4 In: Encyclopedia of Plant and Crop Science (R. Goodman, ed.), Taylor and Francis.

Cvitanich, C., Salcido, M., and Judelson, H. S. (2006) Concerted evolution of a tandemly arrayed family of mating-specific genes in Phytophthora analyzed through interspecific and intraspecific comparisons. Molecular Genetics and Genomics 275, 169-184.

Tani, S. and Judelson, H. S. (2006) Activation of zoosporogenesis-specific genes in Phytophthora infestans involves a seven-nucleotide promoter motif and cold-induced membrane rigidity. Eukaryotic Cell 5, 745-752.

Judelson, H. S., and Senthil, G. (2006) Investigating the role of ABC transporters in multifungicide insensitivity in Phytophthora infestans. Molecular Plant Pathology 7, 17-29.

Blanco, F. A., and Judelson, H. S. (2005) A bZIP transcription factor from Phytophthora interacts with a protein kinase and is required for zoospore motility and plant infection. Molecular Microbiology 56, 638-648.

Randall, T. A., Dwyer, R. A., Huitema, E., Beyer, K., Cvitanich, C., Kelkar, H., Ah Fong, A. M. V., Gates, K., Roberts, S., Yatzkan, E., Gaffney, T., Law, M., Testa, A., Torto, T. , Zhang, M., Zheng, L., Mueller, E., Windass, J., Binder, A. , Birch, P. R. J., Gisi, U., Govers, F., Gow, N. A., Mauch, F., van West, P., Waugh, M., Yu, J., Boller, T., Kamoun, S., Lam, S. T., and Judelson, H. S. (2005) Large-scale gene discovery in the oomycete Phytophthora infestans reveals likely components of phytopathogenicity shared with true fungi. Molecular Plant-Microbe Interactions 18, 229-243.

Tani, S., Kim, K.-S., and Judelson, H. S. (2005) A cluster of NIF transcriptional regulators with divergent patterns of spore-specific expression in Phytophthora infestans. Fungal Genetics and Biology 42, 42-50.

Ah Fong, A., and Judelson, H. S. (2004) The hAT-like DNA transposon, DodoPi, resides in a cluster of retro- and DNA transposons in the stramenopile Phytophthora infestans. Molecular Genetics and Genomics , 271: 577-585.

Tani, S., Yatzkan, E., and Judelson, H. S. (2004) Multiple pathways regulate the induction of genes during zoosporogenesis in Phytophthora infestans. Molecular Plant Microbe Interactions 17, 330-337.

Kim, K. S., and Judelson, H. S. (2003) Sporangia-specific gene expression in the oomycete phytopathogen Phytophthora infestans. Eukaryotic Cell 2, 1376-1385.

Ah Fong, A., and Judelson, H. S. (2003) Cell cycle regulator Cdc14 is expressed during sporulation but not hyphal growth in the fungus-like oomycete Phytophthora infestans. Molecular Microbiology 50, 487-494.

Fabritius, A.-L. and Judelson, H. S. (2003) A mating-induced protein of Phytophthora infestans is a member of a family of elicitors with divergent structures and stage-specific patterns of expression. Molecular Plant-Microbe Interactions 16, 926-935.

Cvitanich, C., and Judelson, H. S. (2003) A gene expressed during sexual and asexual sporulation in Phytophthora infestans is a member of the Puf family of translational regulators. Eukaryotic Cell2, 465-473.

Cvitanich, C., and Judelson, H. S. (2002) Stable transformation of the oomycete, Phytophthora infestans, using microprojectile bombardment. Current Genetics 42, 228-235.

Judelson, H. S., and Roberts, S. (2002) Novel protein kinase induced during sporangial cleavage in the oomycete Phytophthora infestans. Eukaryotic Cell 1, 687-695

Fabritius, A.-L., Cvitanich, C., and Judelson, H. S. (2002) Stage-specific gene expression during mating in Phytophthora infestans. Molecular Microbiology 45, 1057-1066

Randall, T. A., and Judelson, H. S. (2002) Chromosomal heteromorphism and an apparent translocation detected using a BAC contig spanning the mating type locus of Phytophthora infestans. Fungal Genetics and Biology 38, 75-84.

Judelson, H. S. (2002) Sequence variation and genomic amplification of a family of Gypsy-like sequences in the oomycete genus Phytophthora. Molecular Biology and Evolution 19, 1313-1322.

Judelson, H. S., and Tooley, P.W. (2000) Enhanced polymerase chain reaction methods for detecting and quantifying Phytophthora infestans in plants. Phytopathology. 90, 1112-1119.

Judelson, H. S., and Fabritius, A-L. (2000) A linear RNA replicon from the oomycete, Phytophthora infestans. Molecular and General Genetics 263, 395-403.

Randall, T. A., and Judelson, H. S. (1999) Construction of a bacterial artificial chromosome library of Phytophthora infestans and transformation of clones into P. infestans. Fungal Genetics and Biology 28, 160-170.

Judelson, H. S., and Roberts, S. (1999) Multiple loci determining insensitivity to phenylamide fungicides in Phytophthora infestans. Phytopathology 89, 754-760.

van West, P., De Jong, A., Judelson, H. S., Emons, A. M. E., and Govers, F. (1998) The ipiO gene of Phytophthora infestans is highly expressed in invading hyphae during infection. Fungal Genetics and Biology 23, 126-138.

Judelson, H. S., and Yang, G. (1998) Recombination pathways in Phytophthora infestans: polyploidy resulting from aberrant sexual development and zoospore-mediated heterokaryosis. Mycological Reports 102, 1245-1253.

Judelson, H. S., and Randall, T. A. (1998) Families of repeated DNA in the oomycete Phytophthora infestans and their distribution within the genus. Genome 41, 605-615.

Judelson, H. S. (1997) Expression and inheritance of sexual preference and selfing propensity in Phytophthora infestans. Fungal Genetics and Biology 21, 188-197.

Fabritius, A.-L., and Judelson, H. S. (1997) Mating type loci segregate aberrantly in Phytophthora infestans but normally in Phytophthora parasitica: implications for models of mating type determination. Current Genetics 32, 60-65.

Fabritius, A.-L., Shattock, R. C., and Judelson, H. S. (1997) Genetic analysis of metalaxyl insensitivity loci in Phytophthora infestans using linked DNA markers. Phytopathology 87, 1034-1040.

Judelson, H. S. (1997) The genetics and biology of Phytophthora infestans: modern approaches to a historical challenge. Fungal Genetics and Biology 22, 65-76.

Judelson, H. S. (1996) Recent advances in the genetics of oomycete plant pathogens. Molecular Plant-Microbe Interactions 9, 443-449.

Judelson, H. S. and Messenger-Routh, B. (1996) Quantitation of Phytophthora cinnamomi in avocado roots using a species-specific DNA probe. Phytopathology 86, 763-768.

Judelson, H. S. (1996) Chromosomal heteromorphism associated with the mating type locus of the oomycete, Phytophthora infestans. Molecular and General Genetics 252, 155-161.

Judelson, H. S. (1996) Physical and genetic variability at the mating type locus of the oomycete, Phytophthora infestans. Genetics 144, 1005-1013.

Judelson, H. S., Spielman, L. J., and Shattock, R. C. (1995) Genetic mapping and non-Mendelian segregation of mating type loci in the oomycete, Phytophthora infestans. Genetics 141, 503-512.

Judelson, H. S., and Whittaker, S. L. (1995) Inactivation of transgenes in Phytophthora infestans is not associated with their deletion, methylation, or mutation. Current Genetics 28, 571-579.

Judelson, H. S. (1993) Intermolecular ligation mediates efficient cotransformation in Phytophthora infestans. Mol. Gen. Genet. 239, 241-250.

Judelson, H. S., Coffey, M.D., Arredondo, F.R., and Tyler, B.M. (1993) Transformation of the oomycete pathogen Phytophthora megasperma f. sp. glycinea occurs by DNA integration into single or multiple chromosomes. Current Genetics. 23, 211-218.

Judelson, H. S., Dudler, R., Pieterse, C.M.J., Unkles, S.E., and Michelmore, R.W. (1993) Expression and antisense inhibition of transgenes in Phytophthora infestans is modulated by choice of promoter and position effects. Gene (Amsterdam). 133, 63-69.

Judelson, H. S., and Michelmore, R. W. (1992) Temperature and genotype interactions in lettuce downy mildew. Physiological and Molecular Plant Pathology 40, 233-245.

Judelson, H. S., Tyler, B. M., and Michelmore, R. W. (1992) Regulatory sequences for expressing genes in oomycetes. Molecular and General Genetics 234, 138-146.

Judelson, H. S., Tyler, B.M., and Michelmore, R.W. (1991) Stable transformation of the oomycete pathogen, Phytophthora infestans. Molecular Plant-Microbe Interactions. 4, 602-607.

Judelson, H. S., and Michelmore, R. W. (1991) Transient expression of foreign genes in the oomycete Phytophthora infestans using Bremia lactucae regulatory sequences. Current Genetics 19, 453-459.

Judelson, H. S., and Michelmore, R. W. (1990) Highly abundant and stage-specific mRNAs in the obligate pathogen Bremia lactucae. Molecular Plant-Microbe Interactions 3, 225-232.

Judelson, H. S., and Michelmore, R.W. (1989) Structure and expression of a gene encoding heat-shock protein Hsp70 from the Oomycete fungus Bremia lactucae. Gene 79, 207-218.

Judelson, H. S., and Dimond, R.L. (1988) Maturation of asparagine-linked oligosaccharides in Dictyostelium discoideum analyzed with modification-specific probes. Archives of Biochemistry and Biophysics 267, 151-157.

Judelson, H. S., and Dimond, R.L. (1988) Developmental changes in glycosylation and targeting of lysosomal proteins in Dictyostelium discoideum. Differentiation 37, 7-13.

Judelson, H. S., Freeze, H. H., and Dimond, R.L. (1987) Characterization and distribution of multiple antigens on N-linked oligosaccharides of Dictyostelium discoideum proteins. Archives of Biochemistry and Biophysics 253:305-314.

Judelson, H. S., Burns, R. A., and Dimond, R.L. (1987) A locus regulating N-acetylglucosaminidase synthesis during development in Dictyostelium. Developmental Biology 120, 170-176.

Judelson, H. S., and Vogt, V.M. (1980) Accessibility of ribosomal genes to trimethyl psoralen in nuclei of Physarum polycephalum. Molecular and Cellular Biology 2, 211-220.

last updated 9.2015